Dr Yang Wang and colleagues from Vanderbilt University have shown a novel mechanism of cancer development through EGFR negative regulator, LRIG1. LRIG1 negatively regulates EGFR signaling. Image credit: Yang Wang et al. Stem cells are responsible for tissue proliferation and regeneration. Intestinal epithelium, a single layer of cells lining the intestine that separate external and internal environment, is a highly regenerative tissue, with old cells...
