According to a study published last week in the Proceedings of the National Academy of Sciences, dog domestication may have caused harmful genetic changes. Canadian Eskimo dogs. Illustration by John James Audubon and John Bachman (1845-1848). Domesticating dogs from gray wolves more than 15,000 years ago involved artificial selection and inbreeding, but the effects of these processes on dog genomes have been little-studied. “Small population size...