Abdominal (belly) fat is harmful to metabolic health. Exercise training reduces abdominal fat mass, but the underlying mechanisms have not been clear. According to a new study, published in the journal Cell Metabolism, a signaling molecule called interleukin-6 plays a key role in this process. Wedell-Neergaard et al show that in abdominally obese people, exercise-mediated loss of visceral adipose tissue mass requires interleukin-6 (IL-6) receptor...