DNA makes up only half of the material inside chromosomes, according to a new study published in the journal Molecular Cell. Up to 47% of their structure is a mysterious sheath that surrounds the genetic material. Booth et al. develop a microscopy method called 3D-CLEM. Using this approach, they find that a large portion of mitotic chromosomes is not composed of chromatin, challenging classical perceptions of chromosomes. Image credit: Booth et al,...
