Tag Archive for 'Hematopoietic stem cell'

Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. Image credit: Hanna Mikkola Lab, UCLA / Katja Schenke-Layland Lab, University of Tübingen.

Researchers Create Map of Human Blood Stem Cell Development

Apr 19, 2022 by News Staff

A research team led by University of California, Los Angeles scientists has created a single-cell transcriptome map of human hematopoietic tissues from...

Zhao et al demonstrate that HSCs have a back-up system in stressed condition. Both reserve and active stem HSCs are maintained in the bone marrow by specific niches. While the latter are chemo-sensitive, the former survive and restore stem cells, and thereby generate the blood system. Image credit: Zhao et al, doi: 10.1016/j.celrep.2018.12.093.

Blood-Forming Stem Cells Have Back-Up System in Stressed Condition, New Study Shows

Jan 16, 2019 by News Staff

Blood-forming (hematopoietic) adult stem cells reside deep in the bone marrow and are responsible for regenerating the body’s blood supply including...