Tag Archive for 'Integrin'

This diagram shows how the effects of Gαs-coupled agonists on T cells can be influenced by sleep or disease. Image credit: Dimitrov et al, doi: 10.1084/jem.20181169.

Study: Sleep Improves Ability of Human Immune Cells to Bind to Their Targets

Feb 18, 2019 by News Staff

A new study published online in the Journal of Experimental Medicine describes how sleep can fight off an infection, whereas other conditions, such as...

Fever is an evolutionarily conserved response in both endothermic and ectothermic species and confers survival benefits during infection and injury. Lin et al identify that the Hsp90-a4-integrin axis serves as a thermal sensory pathway that responds to fever to promote T cell trafficking and enhance immune surveillance during infection. Image credit: Lin et al, doi: 10.1016/j.immuni.2018.11.013.

Fever Helps Fight Off Infection by Altering Immune Cells

Jan 16, 2019 by News Staff

According to a study published in the journal Immunity, fever alters surface proteins on immune cells to make them better able to travel via blood vessels...