Tag Archive for 'Multiple sclerosis'

Flavonoid-rich cocoa could reduce fatigue in multiple sclerosis patients. Image credit: Steve Buissinne.

Flavonoid-Rich Cocoa Could Reduce Multiple Sclerosis-Related Fatigue

Mar 6, 2019 by News Staff

Flavonoids are a group of natural polyphenolic compounds with variable structures. They are found in fruits, vegetables, grains, bark, roots, stems, flowers,...

Plasma cells (PC) are found in the central nervous system of multiple sclerosis patients, yet their source and role in multiple sclerosis remains unclear. Rojas et al find that some PC in the central nervous system of mice with experimental autoimmune encephalomyelitis (EAE) originate in the gut and produce immunoglobulin A (IgA). Moreover, the researchers show that IgA + PC are dramatically reduced in the gut during EAE, and likewise, a reduction in IgA-bound fecal bacteria is seen in multiple sclerosis patients during disease relapse. Image credit: Rojas et al, doi: 10.1016/j.cell.2018.11.035.

Gut-Derived Immune Cells Reduce Brain Inflammation in Multiple Sclerosis

Jan 8, 2019 by News Staff

Studying mice and samples from multiple sclerosis patients, a research team led by University of Toronto scientists found that gut-derived immunoglobulin-A-(IgA)...

Under a high magnification of 12,960x, this SEM image revealed some of the morphologic details displayed by a number of joined, Gram-negative, rod-shaped, Escherichia coli bacteria. Image credit: Janice Haney Carr, CDC.

New Study Reveals Link between Gut Microbiota and Multiple Sclerosis

Oct 15, 2018 by News Staff

Multiple sclerosis is an immune-mediated autoimmune disease of the central nervous system that develops in genetically susceptible individuals and requires...

Lesional psoriatic skin. Image credit: Wu et al, doi: 10.1371/journal.pone.0005227.

Compound Derived from Immune Cells Treats Psoriasis in Mice

May 8, 2018 by News Staff

A modified form of a compound called itaconate suppresses an inflammatory pathway that is overactive in many autoimmune diseases, suggesting that it may...

Main symptoms of multiple sclerosis. Image credit: Mikael Häggström.

48 New Genetic Variants Linked to Multiple Sclerosis

Oct 4, 2013 by News Staff

Genetic researchers reporting in the journal Nature Genetics have discovered an additional 48 genetic variants influencing the risk of developing multiple...