Ferroptosis, which is caused by a buildup of iron in cells, appears to be a major mechanism of white matter injury in Alzheimer’s disease and vascular dementia, according to a new study. White matter degenerating microglia are a novel therapeutic target to potentially reduce the impact of white matter injury and myelin loss on the progression of cognitive impairment. Image credit: Miroslaw Miras. “This is a major finding,” said Professor Stephen...
