Tag Archive for 'Autoimmune disease'

Ali et al. explored the extent to which oral intake of a whole-ginger extract would similarly impact neutrophils in both autoimmune mice and healthy humans. Image credit: Siala.

Ginger Supplements May Help Reduce Inflammation in Autoimmune Diseases

Sep 27, 2023 by News Staff

In a new clinical trial, scientists from the University of Michigan, Ann Arbor and the University of Colorado School of Medicine found that oral administration...

A model of a Neanderthal man in modern clothing. Image credit: H. Neumann / Neanderthal Museum.

New DNA Study Points to Importance of Balancing Selection in Human Evolution

Feb 22, 2023 by News Staff

Different genetic traits can be beneficial (for example, fending off disease) or harmful (making humans more susceptible to illness), depending on the...

Genomic analyses of wildtype and TET-deficient Treg cells, and iTreg cells treated with the TET activator vitamin C, show that TET proteins are essential for the maintenance of Treg signatures and IL-2/STAT5 signaling. Image credit: Yue et al., doi: 10.15252/embr.202152716.

Vitamin C is Key Ingredient for Immune Cell Function, Study Shows

Jul 22, 2021 by News Staff

Regulatory T cells (Tregs) help control inflammation and autoimmunity in the body. These cells are so important that scientists are working to generate...

Ginger is known to have anti-inflammatory and anti-oxidative effects, and has traditionally been used as an herbal supplement in the treatment of various chronic diseases. Image credit: Joseph Mucira.

Ginger-Derived Compound May Help Prevent Lupus and Antiphospholipid Syndrome

Jan 7, 2021 by News Staff

In a study published in the journal JCI Insight, 6-gingerol, the most abundant bioactive compound of ginger root, lowered autoantibody production and helped...

Plasma cells (PC) are found in the central nervous system of multiple sclerosis patients, yet their source and role in multiple sclerosis remains unclear. Rojas et al find that some PC in the central nervous system of mice with experimental autoimmune encephalomyelitis (EAE) originate in the gut and produce immunoglobulin A (IgA). Moreover, the researchers show that IgA + PC are dramatically reduced in the gut during EAE, and likewise, a reduction in IgA-bound fecal bacteria is seen in multiple sclerosis patients during disease relapse. Image credit: Rojas et al, doi: 10.1016/j.cell.2018.11.035.

Gut-Derived Immune Cells Reduce Brain Inflammation in Multiple Sclerosis

Jan 8, 2019 by News Staff

Studying mice and samples from multiple sclerosis patients, a research team led by University of Toronto scientists found that gut-derived immunoglobulin-A-(IgA)...

The C6orf106 gene controls the production of proteins involved in infectious diseases, cancer and diabetes. Image credit: CSIRO.

Critical Immunity-Related Gene Identified

Jul 2, 2018 by News Staff

A team of researchers at the Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia, has identified an ancient gene that plays...

Lesional psoriatic skin. Image credit: Wu et al, doi: 10.1371/journal.pone.0005227.

Compound Derived from Immune Cells Treats Psoriasis in Mice

May 8, 2018 by News Staff

A modified form of a compound called itaconate suppresses an inflammatory pathway that is overactive in many autoimmune diseases, suggesting that it may...

The new study indicates that oral NaHCO3 activates a splenic anti-inflammatory pathway and provides evidence that the signals that mediate this response are transmitted to the spleen via a novel neuronal-like function of mesothelial cells. Image credit: Sci-News.com.

Drinking Baking Soda Daily May Help Reduce Inflammation Caused by Autoimmune Diseases

Apr 27, 2018 by News Staff

A team of researchers at Augusta University has shown that when rats or healthy people drink a solution of baking soda (sodium bicarbonate, NaHCO3), it...

Enterococcus gallinarum (orange dots) in liver tissue. Image credit: Vieira et al.

Study: Gut Bacteria Trigger Autoimmune Disease

Mar 12, 2018 by News Staff

Enterococcus gallinarum, a species of bacterium found in the small intestines of humans and mice, can travel to other organs and trigger an autoimmune...

According to Soderquest et al, T-bet plays an important role in coordinating the body’s immune responses. Image credit: Werbe Fabrik.

‘Molecular Switch’ that Causes Mucosal Autoimmune Diseases Discovered

Feb 21, 2017 by Enrico de Lazaro

According to an international team of researchers led by University College London and King’s College London, the discovery of a ‘molecular switch’...