Tag Archive for 'Catechin'

Tea catechins are produced following the flavonoid metabolic pathways, regulated by multiple enzymes and transcription factors. Image credit: Li et al., doi: 10.1093/hr/uhae178.

New Study Sheds Light on Catechin Biosynthesis in Tea Plants

Sep 23, 2024 by News Staff

Catechins are the major active compounds present in the tea plant (Camellia sinensis), the main industrial crop cultivated worldwide. Tea catechins are...

Hodges et al. found that consuming green tea extract for four weeks can reduce blood sugar levels and improve gut health by lowering inflammation and decreasing gut permeability. Image credit: Sci-News.com.

Green Tea Extract Consumption May Help Reduce Blood Sugar Levels, Improve Gut Health

Jul 26, 2022 by News Staff

Dietary interventions with catechin-rich green tea extract confections in healthy adults and persons with with metabolic syndrome decreased fasting glucose...

A concentration of 2.5 μM EGCG and ECG enhanced health- and lifespan as well as stress resistance in Caenorhabditis elegans. Catechins hampered mitochondrial respiration in Caenorhabditis elegans after 6-12 hrs and the activity of complex I in isolated rodent mitochondria. The impaired mitochondrial respiration was accompanied by a transient drop in ATP production and a temporary increase in ROS levels in Caenorhabditis elegans. After 24 hrs, mitochondrial respiration and ATP levels got restored, and ROS levels even dropped below control conditions. The lifespan increases induced by EGCG and ECG were dependent on AAK-2/AMPK and SIR-2.1/SIRT1, as well as on PMK-1/p38 MAPK, SKN-1/NRF2, and DAF-16/FOXO. Long-term effects included significantly diminished fat content and enhanced SOD and CAT activities, required for the positive impact of catechins on lifespan. Image credit: Tian et al., doi: 10.18632/aging.203597.

Study: Green Tea Catechins Extend Health- and Lifespan, Reduce Fat Content in Model Organism

Oct 27, 2021 by Enrico de Lazaro

Green tea is one of the most widely consumed beverages worldwide. Green tea catechins are associated with a delay in aging. In experiments performed in...

Cocoa and green tea flavonoids may be beneficial in the nutritional management of age-related deterioration of the neuromuscular system. Image credit: Sci-News.com.

Green Tea and Cocoa-Enriched Diet May Help Prevent Age-Associated Neuromuscular Changes

Sep 2, 2021 by Natali Anderson

A new study in mice provides insights into the use of green tea and cocoa flavonoids as nutritional interventions for the treatment of aging-related neuromuscular...

An activation of the vascular and neuronal KCNQ5 potassium channel contributes significantly to vasodilation by both green and black tea; the tea polyphenols ECG and EGCG are major contributors to this effect, via hyperpolarization of the voltage dependence of KCNQ5 activation; ECG and EGCG or optimized derivatives of these compounds are candidates for future anti-hypertensive drug development. Image credit: Sci-News.com.

Two Tea Compounds Found to Relax Blood Vessels

Mar 10, 2021 by News Staff

A team of researchers from the University of California, Irvine and the University of Copenhagen has found that two polyphenol compounds found in green...

Zhao et al. provide insights into the mechanisms for EGCG’s anticancer activity and identifies p53 N-terminal domain as a target for cancer drug discovery through dynamic interactions with small molecules. Image credit: Sci-News.com.

Green Tea Compound Stabilizes ‘Guardian of the Genome’ Protein

Feb 17, 2021 by News Staff

Epigallocatechin-3-gallate (EGCG), a polyphenol found in the leaves of green tea (Camellia sinensis), may increase levels of the natural anti-cancer protein...

Flavanols are a large group of flavonoids, which include catechin, epicatechin, epigallocatechin, epicatechin gallate and epigallocatechin gallate. They are found in teas, cocoa, fava beans, red wine, and many fruits, particularly in the skins of grapes, apples, and blueberries. Image credit: Marijana.

Flavanol-Rich Diet Could Help Lower Blood Pressure

Oct 22, 2020 by News Staff

Consuming a high-flavanol diet was associated with a significantly lower systolic and diastolic blood pressure and was inversely associated with blood...

Green tea polyphenols have the potential to improve skeletal muscle metabolism in obese mice by improving glucose homeostasis, reducing lipid peroxidation, and increasing rate limiting enzymes of oxidative phosphorylation. Image credit: Andi Ketaren.

Green Tea Consumption Improves Metabolism, Overall Health in Obese Mice: Study

Mar 19, 2019 by News Staff

In a study published in the Journal of Nutritional Biochemistry, mice fed a diet of 2% green tea extract fared far better than those that ate a diet without...

According to Rowley IV et al, cocoa compounds have beneficial effects on beta-cell function. Image credit: Pernilla Klockars.

Study: Cocoa Compounds Help Cells Release More Insulin

Sep 1, 2017 by News Staff

When a person has diabetes, their body either doesn’t produce enough insulin or doesn’t process blood sugar properly; at the root of that is the failure...

Tea Tree Genome Sequenced

May 2, 2017 by News Staff

A multi-institutional team of researchers from China and the United States has sequenced the genome of the cultivated tea tree (Camellia sinensis). A tea...