Tag Archive for 'Fat'

Hops (Humulus lupulus). Image credit: Elisa Klickblick.

Two Compounds Derived from Hops Attenuate High-Fat Diet-Induced Hepatic Steatosis: Study

Jun 17, 2021 by News Staff

Xanthohumol, a prenylated flavonoid produced by hops (Humulus lupulus), and its synthetic derivative, tetrahydroxanthohumol, can mitigate the diet-induced...

Diet-induced obesity results in Paneth cell dysfunction in humans and mice. Image credit: Liu et al., doi: 10.1016/j.chom.2021.04.004.

Western Diet Causes Damage to Immune Cells in Gut, Study Shows

May 19, 2021 by News Staff

Paneth cells, immune cells in the gastrointestinal epithelia, modulate innate immunity and infection. In Crohn’s disease, genetic mutations together...

Zhou & Hyppönen observed a positive dose-dependent association between self-reported coffee intake and plasma concentration of low-density-lipoprotein cholesterol, total cholesterol and apolipoprotein B, with the highest lipid levels seen among participants reported drinking over 6 cups/day. Image credit: Ermal Tahiri.

Heavy Coffee Consumption May Increase Cardiovascular Disease Risk

Feb 25, 2021 by News Staff

Long-term heavy coffee consumption (six or more cups a day) may lead to unfavourable lipid (fat) profile, which could potentially increase individuals’...

Brown Fat May Protect against Metabolic and Cardiovascular Diseases

Jan 5, 2021 by News Staff

White fat stores excess energy, whereas brown and beige fat are thermogenic and dissipate energy as heat. But it is unclear whether individuals with ample...

Bifidobacterium longum APC1472 has promising potential to be developed as a valuable supplement in reducing specific markers of obesity and is poised to have significant relevance in conditions of heightened blood glucose, such as type 2 diabetes. Image credit: Ali et al., doi: 10.5281/zenodo.1333400.

New Strain of Bifidobacterium May Help Improve Metabolic and Mental Health

Dec 22, 2020 by News Staff

The supplementation of a novel strain of Bifidobacterium longum, designated APC1472, in otherwise healthy overweight and obese individuals reduced their...

White fat cells (adipocytes) activate the lipolysis pathway to produce the free fatty acids that are used as heating fuel by brown adipose tissue. Nayak et al show that OPN3 is required for blue-light-enhanced activation of the lipolysis pathway. This explains the low body temperature of OPN3 mutant mice. Image credit: Nayak et al, doi: 10.1016/j.celrep.2019.12.043.

Fat Cells Can Sense Light, Animal Study Shows

Jan 28, 2020 by News Staff

Light exposure regulates how two kinds of fat cells (adipocytes) work together to produce the raw materials that all other cells use for energy, according...

An enteroendocrine cell (green) lies within the epithelium (red) that lines the intestines of a zebrafish larvae. Image credit: Lihua Ye.

Study: High-Fat Meal Can Silence Communication between Intestine and Rest of the Body

Dec 18, 2019 by News Staff

According to a new study performed in zebrafish (Danio rerio), a high-fat meal can shut down the communication between the enteroendocrine cells —...

Elliot et al show that fatty tissue is present within the airway wall and is related to BMI, wall thickness and the number of inflammatory cells. The accumulation of airway fatty tissue in overweight individuals may therefore contribute to airway pathophysiology. Image credit: Kalhh.

Fatty Tissue Accumulates in Airways of Overweight and Obese People, New Study Finds

Oct 21, 2019 by News Staff

According to a new study published in the European Respiratory Journal, fatty tissue accumulates within the airway walls of people who are overweight or...

Dietary fructose, but not glucose, supplementation of high-fat diet (HFD) impairs mitochondrial size, function, and protein acetylation, resulting in decreased fatty acid oxidation and development of metabolic dysregulation. Image credit: Softic et al, doi: 10.1016/j.cmet.2019.09.003.

High-Fat Plus Fructose Diet Alters Size and Function of Liver Mitochondria, New Study Says

Oct 2, 2019 by News Staff

A research team led by Harvard Medical School scientists has found that high levels of fructose — but not glucose — in the high-fat diet inhibit...

Stonehenge’s Builders Transported Megaliths Using Tallow, Says Archaeologist

Jul 17, 2019 by News Staff

Lipid (fat) residues identified in Grooved Ware pottery from Durrington Walls, near Stonehenge, have been interpreted as evidence for large-scale feasting...

Diet that restricts glucose may help brain function. Image credit: Cattalin.

Atkins-Style Diet May Improve Brain Function and Memory in Older Adults

Jul 2, 2019 by News Staff

A modified Atkins diet (very low carbohydrates and extra fat) may improve brain function and episodic memory, according to a small study of 14 older adults...

After eating a low-carb diet, more than half the participants saw their metabolic syndrome reversed even though they were fed diets that intentionally contained enough calories to keep their weight stable. Image credit: Hyde et al, doi: 10.1172/jci.insight.128308.

Low-Carb Diet Benefits People with Metabolic Syndrome Independent of Weight Loss

Jun 24, 2019 by News Staff

A new study published in the Journal of Clinical Investigation Insight shows that metabolic syndrome — a cluster of factors that also put people...

$Overview of observed standardized regression coefficients (b values) for the associations between total body fat and fractional anisotropy (FA)- and mean diffusivity (MD)-based DTI tracts for men and women. Standardized regression coefficients reflect the standard deviation (SD) change in FA and MD, respectively, per standard deviation (6.5% in women and 5.5% in men) change in total body fat. Results were adjusted for age, ethnicity, Townsend deprivation index, assessment center (baseline visit and imaging visit), smoking, alcohol use, diabetes, cardiovascular disease, and intracranial volume. Image credit: Dekkers et al, doi: 10.1148/radiol.2019181012.$