Tag Archive for 'UCP1'

Yee Tan et al. discovered a human commensal bacterium, Clostridium immunis, which prevents and treats obesity in mice by secreting a phosphocholine-modified exopolysaccharide (EPS). Image credit: Yee Tan et al., doi: 10.1016/j.chom.2026.08.018.

Sugar Molecule Made by Gut Bacterium Can Shrink Visceral Fat in Mice

Sep 28, 2026 by Natali Anderson

Clostridium immunis, a human gut bacterium, secretes a large sugar molecule that can shrink visceral fat and curb weight gain in mice, according to a paper...

Gaudry et al demonstrate that members of various lineages (for example, cetaceans, horses, woolly mammoths, Steller’s sea cows) evolved extreme cold hardiness in the absence of UCP1-mediated thermogenesis. Image credit: Mauricio Anton.

Single Gene Linked to Evolutionary Rise of Multiple Mammalian Lineages

Jul 17, 2017 by News Staff

Ancient, independent inactivations of the ucp1 gene, which encodes the uncoupling protein 1, or UCP1 (essential for thermogenesis in brown fat), were a...