About 8% of the human genome is composed of endogenous retroviruses. According to a new study published in the journal Cell Reports, these retroviruses may have played a significant role in the development of the human brain as well as in various neurological diseases, such as ALS, schizophrenia and bipolar disorder. Brattas et al. report that ERVs are bound by TRIM28 in human neural progenitor cells. This results in the establishment of local heterochromatin...
