Scientists at the Yale University School of Medicine have proposed an explanation for how Salmonella Typhi, the bacterium that causes typhoid fever, kills 200 thousands people every year. This SEM image shows chronic Salmonella Typhi biofilm formation on cholesterol gallstones (Robert Crawford et al, 2010) Typhoid fever is one of the oldest documented diseases known to have afflicted mankind but what makes it so lethal has remained a mystery for centuries....
