Tag Archive for 'Minocycline' | Sci.News

Müller et al investigated the physicochemical process of extracellular matrix calcification in both physiological (bone) and pathological (vascular calcification) contexts; they found that oxidative stress-induced poly(ADP-ribose) nucleates calcium phosphatemineral crystals on extracellular matrix substrates and that calcification is inhibited by poly(ADP-ribose) polymerase (PARP) enzyme inhibitors. Image credit: Müller et al, doi: 10.1016/j.celrep.2019.05.038.

Molecule Normally Associated with DNA Repair Plays Central Role in Hardening of Arteries: Study

Jun 21, 2019 by News Staff

A new study, published in the June 11 issue of the journal Cell Reports, found that poly(ADP ribose), or PAR, a molecule once thought only to exist inside...