Tag Archive for 'Reward circuit' | Sci.News

Using an interventional study in healthy, normal-weight participants, Thanarajah et al. demonstrate that, independent of body weight gain and alterations in metabolic markers, exposure to high-fat/high-sugar food: (i) reduces preferences for low-fat food, (ii) plays a critical role in up-regulating brain responses to anticipation and consumption of highly palatable, energy-dense food, and (iii) has a generalized effect on the neuronal encoding of prediction errors in the context of associative learning and independent of food rewards. Taken together, repeated consumption of high-fat/high-sugar relative to isocaloric low-fat/low-sugar food, and in the absence of changes in body weight or metabolic state, can rewire brain circuits and thereby induce neurobehavioral adaptations. Hence, changing the food environment and reducing the availability of energy-dense high-fat/high-sugar food items is pivotal to combating the obesity pandemic. Image credit: Thanarajah et al., doi: 10.1016/j.cmet.2023.02.015.

Daily Consumption of Sweet and Fatty Snacks Alters Our Reward Circuits: Study

Mar 23, 2023 by News Staff

Western diets rich in fat and sugar promote excess calorie intake and weight gain; however, the underlying mechanisms are unclear. To close this gap, researchers...