Tag Archive for 'Bleeding'

Schematic overview of the mechanism of action of the implemented snake venom proteins. Ecarin, a procoagulant snake venom protein bypasses the activation of series of clotting factors via intrinsic and extrinsic clotting pathway and directly activates prothrombin to thrombin thereby producing a fibrin blood clot. Once the clot is formed, clot breakdown (fibrinolysis) is initiated by the activation of plasminogen mainly by tissue plasminogen activator (tPA), forming active plasmin which proteolytically acts on the fibrin blood clot. Textilinin, an antifibrinolytic snake venom protein binds to plasmin with high specificity and inhibits the action of plasmin, stabilizing the fibrin blood clot. Image credit: Yegappan et al., doi: 10.1002/adhm.202200574.

Researchers Create Snake Venom Hydrogel that Rapidly Stops Uncontrolled Bleeding

Jun 20, 2022 by News Staff

The newly-developed rapid wound sealant is composed of two snake venom proteins: ecarin, which rapidly initiates blood clotting, and textilinin, which...

Khan et al. performed a meta-analysis of 38 randomized controlled trials of omega-3 fatty acids, stratified by EPA monotherapy and EPA+DHA therapy. Image credit: Sci-News.com.

Omega-3 Fatty Acids Improve Cardiovascular Outcomes, Review Says

Jul 8, 2021 by Enrico de Lazaro

In a systematic review and meta-analysis of 38 randomized controlled trials comprising 149,051 participants, omega-3 fatty acids — such as eicosapentaenoic...

Among patients with stable atherosclerotic vascular disease, those assigned to rivaroxaban (2.5 mg twice daily) plus aspirin had better cardiovascular outcomes and more major bleeding events than those assigned to aspirin alone. Image credit: Val-gb.

COMPASS Study: Combination of Rivaroxaban and Aspirin Works Best for Heart Diseases

Aug 29, 2017 by News Staff

A major new study has found that the combination of two drugs — rivaroxaban and aspirin — is superior to aspirin alone in preventing further...