Tag Archive for 'Blood clot'

Schematic overview of the mechanism of action of the implemented snake venom proteins. Ecarin, a procoagulant snake venom protein bypasses the activation of series of clotting factors via intrinsic and extrinsic clotting pathway and directly activates prothrombin to thrombin thereby producing a fibrin blood clot. Once the clot is formed, clot breakdown (fibrinolysis) is initiated by the activation of plasminogen mainly by tissue plasminogen activator (tPA), forming active plasmin which proteolytically acts on the fibrin blood clot. Textilinin, an antifibrinolytic snake venom protein binds to plasmin with high specificity and inhibits the action of plasmin, stabilizing the fibrin blood clot. Image credit: Yegappan et al., doi: 10.1002/adhm.202200574.

Researchers Create Snake Venom Hydrogel that Rapidly Stops Uncontrolled Bleeding

Jun 20, 2022 by News Staff

The newly-developed rapid wound sealant is composed of two snake venom proteins: ecarin, which rapidly initiates blood clotting, and textilinin, which...

Kim et al developed robotic thread that can be steered magnetically and is small enough to work through narrow spaces such as the vasculature of the human brain; the researchers envision the technology may be used in the future to clear blockages in patients with stroke and aneurysms. Image credit: MIT.

Thread-Like Robot Could Deliver Clot-Reducing Therapies

Sep 2, 2019 by News Staff

A team of researchers at the Massachusetts Institute of Technology (MIT) has developed a thread-like ferromagnetic robot that can glide through complex...

Chang et al found a significant association between varicose veins and DVT. The illustration shows how a varicose vein forms in a leg. Image credit: National Heart Lung and Blood Institute / Jmarchn / CC BY-SA 3.0.

Varicose Veins Linked to Increased Risk of Deep Venous Thrombosis

Mar 2, 2018 by Enrico de Lazaro

According to an observational study published in the journal JAMA, varicose veins may be a warning sign of a type of blood clot known as a deep venous...