Tag Archive for 'Cas9'

With over a million species described, insects are a treasure trove of diversity and represent boundless possibilities as research tools for answering fundamental questions in biology. Current approaches for insect gene editing require microinjection of materials into early embryos, which is highly challenging in most species. Shirai et al. established and optimized a simple and efficient method for insect gene editing by adult injection, which can be readily implemented in any laboratory and directly applied to a great diversity of non-model insect species. Image credit: Shirai et al., doi: 10.1016/j.crmeth.2022.100215.

Scientists Develop New CRISPR Method for Insect Gene Editing

May 18, 2022 by News Staff

Current approaches for insect gene editing require microinjection of materials into early embryos. This severely limits the application of gene editing...

An image illustrating how the Cas9 protein rearranges itself (indicated by the arrow) to enable the ‘scissoring’ action for cutting DNA. Image credit: Zhu et al, doi: 10.1038/s41594-019-0258-2.

Researchers Capture High-Resolution Images of Active Cas9 Enzyme

Jul 11, 2019 by News Staff

Using a technique called cryogenic electron microscopy (cryo-EM), a team of scientists from the United States and Canada has captured atomic-level, 3D...