Tag Archive for 'Enterocyte'

Transmission electron microscopy analysis of SARS-CoV-2 infected intestinal organoids: (a to h) overview of an intact organoid (a) showing the onset of virus infection (b to d) at different stages of the viral lifecycle, i.e., early double membrane vesicles (DMVs); (e), asterisk, initial viral production in the Golgi apparatus (f and g) and complete occupation of virus particles inside the endomembrane system (h); (i to k) extracellular viruses are observed in the lumen of the organoid (i), and are found at the basal (j) and apical side (k) alongside the microvilli (arrows). Scale bars - 10 μm (a), 2.5 μm (b to d), 250 nm (e), (f), and (h to k) and 100 nm (g). (l to q) Overview of an organoid (l) showing severely infected cells (m and o), disintegrated cells (o) and stressed cells as evident from the atypical nucleoli (p); intact cells reveal DMV areas of viral replication (p), asterisks, and infected Golgi apparatus (q); (r) extracellular clusters of viruses. Scale bars - 10 μm (l), 2.5 μm (m to p) and 250 nm (p to r). Image credit: Lamers et al, doi: 10.1126/science.abc1669.

SARS-CoV-2 Coronavirus Can Infect Gut Enterocytes

May 5, 2020 by News Staff

SARS-CoV-2, a novel coronavirus that causes the COVID-19 disease, can infect enterocytes in the intestine and multiply there, according to a study by researchers...

Colorized scanning electron micrograph of an apoptotic cell (red) infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image credit: NIAID.

Study Reveals New Clues about Biology of COVID-19

Apr 22, 2020 by News Staff

A new study published in the journal Cell pinpoints the likely cell types SARS-CoV-2, a new coronavirus behind the COVID-19 disease, infects; it also shows...