Tag Archive for 'Signaling molecule' | Sci.News

Liu et al. show that in normal mouse skin, Scube3 is expressed only in dermal papillae of growing, but not in resting follicles. SCUBE3 protein microinjection is sufficient to induce new hair growth, and pharmacological TGF-β inhibition rescues mutant hair hyper-activation phenotype. Moreover, dermal-papilla-enriched expression of SCUBE3 and its growth-activating effect are partially conserved in human scalp hair follicles. Image credit: Liu et al., doi: 10.1016/j.devcel.2022.06.005.

Newly-Discovered Signaling Molecule Stimulates Hair Multiplication and Growth

Jul 1, 2022 by News Staff

SCUBE3 potently stimulates hair growth and may offer a therapeutic treatment for androgenetic alopecia. Liu et al. show that in normal mouse skin, Scube3...