Tag Archive for 'Placebo'

Habitual coffee consumers justify their life choices by arguing that they become more alert and increase motor and cognitive performance and efficiency; however, these subjective impressions still do not have a neurobiological correlation. Using functional connectivity approaches to study resting-state fMRI data in a group of habitual coffee drinkers, Picó-Pérez et al. show that coffee consumption decreased connectivity of the posterior default mode network (DMN) and between the somatosensory/motor networks and the prefrontal cortex, while the connectivity in nodes of the higher visual and the right executive control network (RECN) is increased after drinking coffee; the data also show that caffeine intake only replicated the impact of coffee on the posterior DMN, thus disentangling the neurochemical effects of caffeine from the experience of having a coffee. Image credit: Sci.News.

Study: Boost from Morning Coffee Can’t Be Replicated with Plain Caffeine

Jun 29, 2023 by News Staff

Plain caffeine only partially reproduces the effects of drinking a cup of coffee, activating areas of the brain that make you feel more alert but not the...

In the study, whole-brain degree count maps, collected before the start of treatment, were used to identify potential brain regional markers for placebo propensity. Group differences in whole-brain maps for degree count (number of connections of any location to the rest of the brain) between placebo responders and non-responders identified four brain regions that differentiated placebo responders from non-responders. The highest significant difference was seen for the right midfrontal gyrus. Abbreviations: r-MFG - right midfrontal gyrus; ACC - anterior cingulate cortex; PCC - posterior cingulate cortex; r-S2/M1 - right secondary somatosensory and primary motor cortex. Image credit: Tétreault P. et al.

New Study Spotlights Brain Region Responsible for Placebo Response in Pain

Oct 31, 2016 by News Staff

A Northwestern University-led team of researchers has identified a region in the brain responsible for the ‘placebo effect’ in pain relief, when a...