Tag Archive for 'Neuropeptide'

The common starfish (Asterias rubens) in Brofjorden at Govik, Lysekil municipality, Sweden. Image credit: W. Carter.

Appetite-Controlling Neurohormone Has Ancient Evolutionary Origin, New Study Shows

Mar 25, 2025 by News Staff

A satiety-inducing molecule called bombesin is not only present in humans and other vertebrates but also in invertebrates such as starfish and their marine...

Stylized structural diagram of oxytocin (DARPA).

Oxytocin Has Heart Healing Properties, New Study Suggests

Oct 2, 2022 by News Staff

New research shows that in zebrafish and human cell cultures, the neurohormone oxytocin — also known as the ‘love hormone’ — stimulates...

$Stinging nettles of the genus Dendrocnide produce potent neurotoxins: (A) sign at a North Queensland National Park advising caution around stinging trees; (B) Dendrocnide excelsa petioles are covered in stinging hairs; (C) scanning electron micrograph of trichome structure on the leaf of Dendrocnide moroides; (D-G) cutaneous reaction resulting from an accidental sting with Dendrocnide moroides documented with an iPhone XR and NEC G120W2 thermal imager, illustrating almost immediate local piloerection (arrowheads in D), development of wheals where stinging hairs penetrate the skin (arrows in E), as well as a long-lasting axon reflex erythema (arrows in F and G) and associated local increase in skin temperature (degrees Celsius); (H) HPLC chromatogram of trichome extract from Dendrocnide excelsa; diamonds indicate nocifensive responses elicited by intraplantar administration of individual fractions in vivo in C57BL6/J mice, with a single late-eluting peak identified as the main pain-causing fraction. Image credit: Irina Vetter, Thomas Durek & Darren Brown, University of Queensland.$

Australian Stinging Trees Make Spider- and Cone Snail-Like Venom

Sep 18, 2020 by News Staff

A team of scientists from the University of Queensland and King’s College London has found that the venom of Australian Dendrocnide trees contains previously...

Model depicting the FLP-7/NPR-22 neuroendocrine axis that underlies the 5-HTergic control of body fat loss. In the nervous system, an integrated 5-HT and octopaminergic circuit stimulates body fat loss. In this study, we report the discovery of a tachykinin signalling system that underlies the 5-HTergic control of body fat loss in C. elegans. The FLP-7 neuroendocrine peptide is secreted from the ASI neurons in response to 5-HT and Oct-mediated signalling. The nutrient sensor AAK-2/AMPK acts in the ASI neurons via the CREB co-regulator CRTC-1 to regulate FLP-7 release in response to 5-HT-encoded signals of food availability. Upon release, FLP-7 acts in the intestine via the NPR-22/NK2R receptor to stimulate the ATGL-1 lipase, which drives fat loss. The identification of FLP-7 and NPR-22 addresses a long-standing question about the molecular basis of the central effects of 5-HT on fat loss in peripheral tissues. Image credit: Lavinia Palamiuc et al, doi: 10.1038/ncomms14237.

Scientists Identify Brain-Signaling Molecule that Triggers Fat Burning

Feb 8, 2017 by News Staff

A research team led by Scripps Research Institute scientist Dr. Supriya Srinivasan has identified a brain hormone that appears to trigger fat burning in...