The Long Interspersed Element-1 (LINE-1) retrotransposon is an ‘ancient genetic parasite’ that has written around one third of the human genome through a ‘copy-and-paste’ mechanism and serves as an active source of genetic diversity and human disease. The human genome contains approximately half a million copies of LINE-1. Image credit: Baldwin et al., doi: 10.1038/s41586-023-06947-z. The LINE-1 retrotransposon, one of the most common elements...
