Tag Archive for 'White matter'

White matter degenerating microglia are a novel therapeutic target to potentially reduce the impact of white matter injury and myelin loss on the progression of cognitive impairment. Image credit: Miroslaw Miras.

New Cause of Alzheimer’s Disease and Vascular Dementia Discovered

Sep 5, 2023 by News Staff

Ferroptosis, which is caused by a buildup of iron in cells, appears to be a major mechanism of white matter injury in Alzheimer’s disease and vascular...

van der Meulen et al. show that both systemic and inhaled glucocorticoid use are associated with an apparently widespread reduction in white matter integrity, which may in part underly the neuropsychiatric side effects observed in patients using glucocorticoids. Image credit: Steve Buissinne.

Glucocorticoid Use Associated with Structural and Volume Changes in White and Gray Matter

Sep 1, 2022 by News Staff

New research from the Leiden University Medical Center shows that both systemic and inhaled glucocorticoids — a class of synthetic steroids —...

Wittfeld et al support the hypothesis that higher cardiorespiratory fitness is associated with larger brain volumes in several brain regions that are not primarily connected to motor-related functions. Image credit: Mabel Amber.

Study: Cardiorespiratory Exercise Improves Brain Health, Decelerates Decline in Gray Matter

Jan 3, 2020 by News Staff

A new study, published in the Mayo Clinic Proceedings, provides evidence of an association between cardiorespiratory fitness — which refers to the...

$Overview of observed standardized regression coefficients (b values) for the associations between total body fat and fractional anisotropy (FA)- and mean diffusivity (MD)-based DTI tracts for men and women. Standardized regression coefficients reflect the standard deviation (SD) change in FA and MD, respectively, per standard deviation (6.5% in women and 5.5% in men) change in total body fat. Results were adjusted for age, ethnicity, Townsend deprivation index, assessment center (baseline visit and imaging visit), smoking, alcohol use, diabetes, cardiovascular disease, and intracranial volume. Image credit: Dekkers et al, doi: 10.1148/radiol.2019181012.$

Excessive Body Fat Linked to Smaller Gray Matter Volume, New Study Says

Apr 25, 2019 by News Staff

A team of researchers in the Netherlands has found that higher levels of body fat are associated with differences in the form and structure of the brain,...