Tag Archive for 'Zika virus'

Zhang et al. observed that Aedes mosquitoes preferred to seek and feed on mice infected by dengue and Zika viruses. Image credit: Zhang et al., doi: 10.1016/j.cell.2022.05.016.

Flaviviruses Make Their Hosts Smell Tastier to Mosquitoes: Study

Jul 1, 2022 by News Staff

New research demonstrates that mosquito-transmitted flaviviruses such as Zika and dengue can manipulate skin microbiota of their hosts to produce a scent...

Sevvana et al achieved a structure of mature Zika virus at 3.1Å resolution; the three envelope glycoproteins are colored yellow, blue and red. Image credit: Madhumati Sevvana / Purdue University.

Researchers Create Most Detailed 3D Model of Zika Virus to Date

Jun 28, 2018 by News Staff

A research team led by Purdue University structural biologist Michael Rossmann was the first to discover the structure of Zika virus — emerging mosquito-borne...

This is a digitally-colorized transmission electron microscopic (TEM) image of Zika virus. Virus particles, here colored blue, are 40 nm in diameter, with an outer envelope, and an inner dense core. Image credit: Cynthia Goldsmith, CDC.

Study: Anti-Dengue Antibody Protects against Zika Virus Infection

Sep 26, 2017 by News Staff

An antibody that protects against dengue virus is also effective against Zika in mice, according to a new study published in the journal Nature Immunology. This...

Zika Virus Kills Glioblastoma Stem Cells, New Research Shows

Sep 6, 2017 by News Staff

In a research paper published this week in the Journal of Experimental Medicine, scientists report that Zika virus could be used to target and kill brain...

Transmission electron micrograph of Zika virus. Virus particles are 40 nm in diameter, with an outer envelope, and an inner dense core. Image credit: Cynthia Goldsmith / CDC.

Newly Discovered Antibody ‘Neutralizes’ Zika Virus, Shows Mouse Study

Nov 11, 2016 by News Staff

A research team led by Vanderbilt University Medical Center scientist Prof. James Crowe, Jr., has isolated a human monoclonal antibody that in a mouse...

Study Casts New Light on Evolution, Spread of Zika Virus

Oct 17, 2016 by News Staff

A team of scientists led by Dr. Massimo Ciccozzi from the University Campus Bio-Medico in Rome, Italy, has modeled the evolutionary development and diversity...

Electron microphotograph shows two Wolbachia cells that have infected a Nasonia wasp. The one to the left is infected with the WO phage, pointed out by the black arrowheads. The one to the right is uninfected. The large dark patch is bacteria DNA that has been degraded by the phage. The image also shows the multiple wasp membranes wrapped around the Wolbachia that the phage must penetrate both to enter and escape from the bacteria. Image credit: Bordenstein Lab, Vanderbilt University.

Biologists Find DNA of Black Widow Spider Toxin in Genome of Bacteriophage

Oct 13, 2016 by News Staff

Biologists at Vanderbilt University have discovered DNA of the black widow spider toxin in the genome of a virus that attacks Wolbachia, a type of symbiotic...

Researchers Sequence Genome of Zika Virus Reference Strain

Sep 7, 2016 by Enrico de Lazaro

Researchers from Germany, French Polynesia and the United Kingdom have successfully sequenced and analyzed the genome of a World Health Organization reference...

Marco Onorati et al. describe the derivation and characterization, including single-cell RNA-seq, of neocortical and spinal cord neuroepithelial stem (NES) cells to model early human neurodevelopment and Zika virus (ZIKV)-related neuropathogenesis. By analyzing human NES cells, organotypic fetal brain slices, and a ZIKV-infected micrencephalic brain, the team shows that ZIKV infects both neocortical and spinal NES cells as well as their fetal homolog, radial glial cells (RGCs), causing disrupted mitoses, supernumerary centrosomes, structural disorganization, and cell death. ZIKV infection of NES cells and RGCs causes centrosomal depletion and mitochondrial sequestration of phospho-TBK1 during mitosis. The scientists also found that nucleoside analogs inhibit ZIKV replication in NES cells, protecting them from ZIKV-induced pTBK1 relocalization and cell death. They established a model system of human neural stem cells to reveal cellular and molecular mechanisms underlying neurodevelopmental defects associated with ZIKV infection and its potential treatment. Image credit: Marco Onorati et al.

Researchers Discover How Zika Virus Causes Fetal Brain Damage

Aug 25, 2016 by News Staff

According to a team of researchers led by Yale University, infection by the Zika virus diverts a key protein necessary for neural cell division in the...

Close-up of North America: parts of the southern U.S., including parts of Florida, Texas and Louisiana, are vulnerable to transmission of Zika virus. Image credit: Abdallah M. Samy et al.

New Map Predicts Spread of Zika Virus

Aug 16, 2016 by Enrico de Lazaro

An international group of scientists led by the University of Kansas has created a detailed map that shows areas of the world most likely to see cases...

Aedes aegypti biting human. Image credit: James Gathany / CDC.

First Confirmed Transmission of Zika Virus by Aedes aegypti Mosquitoes

Jul 26, 2016 by News Staff

Led by University of Texas Medical Branch researcher Prof. Scott Weaver, an international team of scientists is the first to directly connect Aedes aegypti...

Human Vaccine for Zika Virus May Have Potential

Jul 19, 2016 by Rafid Rahman

Transmission electron micrograph of Zika virus, which is a member of the family Flaviviridae. Virus particles are 40 nm in diameter, with an outer envelope,...

The inoculation of viruses into mosquito bite sites is an important and common stage of arbovirus infections. Dr. McKimmie and his colleagues show that inflammation at bite sites aids viral replication and dissemination in vivo, resulting in more severe infection. These findings define additional targets for post-exposure prophylactic intervention. Image credit: Marieke Pingen et al.

Inflammation from Mosquito Bites May Enhance Virus Replication, Dissemination

Jun 22, 2016 by News Staff

According to a mouse study published this week in the journal Immunity, the swelling and irritation that make mosquito bites so unpleasant may provide...

A representation of the surface of Zika virus with protruding envelope glycoproteins (red) shown. Image credit: Devika Sirohi et al / Purdue University.

New Study Reveals Structure of Zika Virus

Apr 1, 2016 by News Staff

A team of researchers led by Purdue University scientists Michael Rossmann and Richard Kuhn is the first to determine the structure of the Zika virus,...