Dietary sugar alters the gut microbiome, setting off a chain of events that leads to metabolic disease, pre-diabetes, and weight gain, according to a new study performed in mice. Kawano et al. show that intestinal microbiota protects against development of obesity, metabolic syndrome, and pre-diabetic phenotypes by inducing commensal-specific Th17 cells. Image credit: Kawano et al., doi: 10.1016/j.cell.2022.08.005. A Western-style high-fat, high-sugar...
